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Skills are fully functional and ready to use. Since built-in skills are indicative, feel free to tune them as needed while we continuously roll out new built-in skills, configuration options, and quality improvements.
MIRA ships with five built-in Skills covering the most common professional domains. Each Skill configures the reasoning engine with domain-specific instructions, a tuned temperature, and iteration limits appropriate for that domain’s requirements.

What a Skill does

When a Skill is active in a session, the reasoning engine:
  • Receives the Skill’s instruction set as part of its system context
  • Applies the Skill’s model overrides (temperature, max iterations, max tokens)
  • Operates within the Skill’s MCP tool allowlist
  • Maintains the Skill’s persona for the full session duration

Built-in Skills

Category: Domain Expert
Icon: 🔬
Colour: Emerald
Optimised for:
  • Pharmaceutical research and drug development pipelines
  • Clinical trial design, ICH/GCP guidelines, FDA 21 CFR compliance
  • Bioinformatics: sequence analysis, NGS pipelines, genomics
  • Statistical analysis for biomedical data (survival analysis, dose-response)
  • Regulatory frameworks: EMA, FDA, ICH Q1–Q14 guidelines
Preferred libraries: biopython, pandas, scipy, statsmodels, lifelinesModel overrides:
OverrideValue
Temperature0.3
Max iterations20
Max tokens8,192

Applying a built-in skill

  1. Click New Chat (⌘N)
  2. In the Skill Picker, click the skill you want
  3. The skill badge appears in the session header
  4. Start your query — the engine operates with the skill’s persona immediately
You can also apply a skill mid-session: click the skill badge in the session header → Change Skill → select a new skill.

Creating Custom Skills

Build your own domain-specific reasoning persona

Skill Scope

Apply a skill to one session or all new sessions automatically